Relationship between duration of untreated psychosis and neurocognition and social cognition in first-episode psychosis

ZX On; S Cotton; J Farhall; E Killackey; K Allott

Journal article

Relationship between duration of untreated psychosis and neurocognition and social cognition in first-episode psychosis

ZX On, S Cotton, J Farhall, E Killackey, K Allott

Schizophrenia Research | ELSEVIER SCIENCE BV | Published : 2016

DOI: 10.1016/j.schres.2016.06.018

Abstract

Cognitive impairment is common in first-episode psychosis (FEP); however, the relationship between duration of untreated psychosis (DUP) and neurocognition remains controversial, and no studies have examined the relationship between DUP and social cognition. This study involved secondary data analysis of baseline data from a randomised controlled trial of supported employment; 122 out 146 young people with FEP met inclusion criteria for this study. Results showed that DUP was not associated with neurocognitive or social cognitive performance. Results do not provide support for the neurotoxicity hypothesis of psychosis.

University of Melbourne Researchers

Susan Cotton Author

Eoin Killackey Author

Kelly Allott Author

Related Projects (1)

FUNCTIONAL RECOVERY IN FIRST EPISODE PSYCHOSIS

People with psychotic illness, even with good treatment, do not tend to make functional recovery. They are over represented among the unempl..

Grants

Awarded by Australian Research Council

Funding Acknowledgements

This work was supported by Australian Rotary Health; the Australian Research Council (LP0883273); Orygen Youth Health Research Centre; a University of Melbourne, Faculty of Medicine, Dentistry and Health Sciences Ronald Philip Griffiths Fellowship to K.A. and National Health and Medical Research Council Career Development Fellowships to E.K. (#1051891) and S.C. (#1061998).